Although Dr. James Andrews estimates that "95 percent" of ACL reconstructive procedures are successful in sports, he sets the number closer to 55 percent among NFL running backs.
Obviously Robert Griffin III isn't a running back, but the Redskins' 2012 pistol-based offense was built on his ability to get out of the pocket and make plays on the run. "So is that a failure of the ACL surgery? No, but that's a failure of that running back losing a step and losing ability to cut on a dime and is not able to play," explained Andrews. "So it's not as rosy as what it might look depending on the high level sport the further you go up the ladder, to try to play football, for example, in the professional league after an ACL operation."