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The White Sox's Ken Griffey Jr. runs to first base Friday after singling in the sixth inning.

Griffey’s stellar debut was a big boost for Vazquez (8-9), who’s been struggling.

The right-hander was 0-4 with a 6.23 ERA his last six starts, and had allowed three or more runs in his last nine starts. He also was coming off a miserable outing against Detroit, allowing six runs and 11 hits in seven innings.

Vazquez was sharp against the Royals, allowing three singles over the first five innings before departing after giving up two runs in the sixth. He allowed two runs and five hits, winning for the first time since June 17 against Pittsburgh. It also was his first road win since beating Seattle on May 10, a span of six starts.

“It was great for him to get that win and great mentally for his next start,” Guillen said. “It’s great for us, too, to give him the ball with confidence.”

Bobby Jenks pitched the ninth for his 22nd save.

Hochevar had a little more trouble.

He was hit hard early and tied a franchise record with three wild pitches. The right-hander has had trouble giving up hits with two outs most of the season — .326 average, 36 RBIs and Friday night was no different.

Hochevar matched a career high by allowing 10 hits in six innings, giving up all four runs with two outs.

“Overall it was an OK performance,” Royals manager Trey Hillman said. “I’m still disappointed with the two-out runs, especially with the three-spot (in the sixth). He’s got to do a better job of controlling the damage. Those crooked numbers hurt you and they hurt us tonight.”

Notes: Griffey wore No. 17 even after Swisher agreed to give up No. 30, Griffey’s number in Cincinnati. “I don’t want to be a disruption to the team and I’ve heard Nick is a little out there, so I’m going to stick with 17 and be happy with it,” Griffey said. ... Royals RF Jose Guillen was a last-minute scratch due to a sore hip flexor. ... Royals 2B Mark Grudzielanek had to leave the game in the ninth inning after colliding with first baseman Ross Gload on a popup down the line. X-rays on his right ankle were negative and Hillman said he’d be evaluated on Saturday.

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