updated 3:20 p.m. ET June 27, 2008

WIMBLEDON, England - Top-seeded Ana Ivanovic was knocked out in the third round of Wimbledon on Friday by 133rd-ranked Zheng Jie of China, extending a spate of stunning upsets at the All England Club.

Ivanovic, who took over the No. 1 ranking after winning the French Open earlier this month, slumped to a 6-1, 6-4 loss to the wild-card entry and doubles specialist.

Two-time women’s champion Serena Williams dispatched 2006 winner Amelie Mauresmo 7-6 (5), 6-1, extending her supremacy over the Frenchwoman to a career record of 10-2.

Ivanovic, who saved two match points before overcoming Nathalie Dechy in three sets on Wednesday, had no answer for the hard-hitting Zheng.

“It’s a surprise for me,” said the 24-year-old Zheng, who won the Wimbledon doubles title in 2006. “Thanks to Wimbledon, (which) gave me a wild card. I just tried my best and had to keep going, going.”

It was the earliest exit by a women’s top-seeded player at Wimbledon since Martina Hingis lost in the first round to Jelena Dokic in 2001.

Ivanovic went out a day after 2004 champion and third-seeded Maria Sharapova was ousted by 154th-ranked Alla Kudryavtseva and two-time men’s runner-up Andy Roddick was bounced by Janko Tipsarevic. A day earlier, Australian Open champion and No. 3-ranked Novak Djokovic fell to Marat Safin.

Ivanovic committed 17 unforced errors, converted only one of seven break-point chances and lost serve four times. She could lose the No. 1 ranking depending on how far No. 2 Jelena Jankovic and No. 4 Svetlana Kuznetsova advance in the tournament.

The match ended with Zheng’s serve hitting the service line and Ivanovic shanking her forehand return into the Court 1 stands.

Special feature Without a Wimbledon championship Take a look at the best tennis players never to win at the All England Club NBCSports.com

“She played really well today and it was a tough match for me,” Ivanovic said. “I’m disappointed with my loss but I still look at it as a learning experience.

“It was a very emotional last couple of weeks for me and it took a bit of a toll,” she added. “I didn’t have great preparation.”

Zheng has won 11 tour doubles titles, including the 2006 Wimbledon and Australian Open championships with Yan Zi. She has captured three career singles titles, in relatively small events at Hobart in 2005 and Estoril and Stockholm in 2006.

Slide show   The Week in Sports Pictures Fireworks, crash landings, Wimbledon theatrics and more. more photos

In 2004, Zheng reached the round of 16 at the French Open to become the first Chinese woman to make the fourth round of a Grand Slam. She reached a career high singles ranking of No. 27 in 2006.

Zheng will play singles and doubles for China at the Beijing Olympics in August.

“I felt today the match gave me more belief for the Olympics,” she said.

MORE FROM TENNIS

Tennis Section Front

2 arrested for stalking Indian tennis star Mirza Blake to play 6-foot-10 Karlovic in Davis Cup Safin dropped from singles matchup with Israel Two-time defending Newport champ Santoro wins Tennis player suspended, fined for racial abuse Dulko saves more match points to make Bastad semis   Video: Venus gives back to kids   Video: 4-year-old phenom dazzles tennis world Interactive: Building the perfect tennis player ATP, WTA scores, schedules Tennis Section Front   Add Tennis headlines to your news reader: