“It’s a new team. There’s no quit in us,” he said. “In the past the game might have got out of hand. But now we expect to win football games, no matter who we are playing, no matter who is injured.”

The Texans had a chance to cut the lead to seven with about 5 minutes left in the third quarter when a 74-yard punt return by Jones got Houston to the Indianapolis 29. But on the next play, Schaub threw into triple coverage and was intercepted by Gary Brackett.

Peyton Manning found Reggie Wayne for a 64-yard pass, but was sacked on third down and the Colts settled for a field goal that made it 27-10.

In the third quarter, a pass from Schaub bounced off the hands of Jones and Rocky Boiman made a diving interception. Four plays later, Addai bolted past DeMarcus Faggins and into the corner of the end zone for an 8-yard score to make it 24-10.

The Colts took their first lead when Addai jumped over a diving Faggins for a 4-yard touchdown run in the second quarter to make it 14-10. It capped an 11-play, 65-yard drive.

Houston used a 33-yard field goal by Kris Brown to go ahead 10-7 early in the second quarter. Green caught a short pass and was tackled after a 9-yard gain by Colts safety Bob Sanders on the play before the field goal. Green hopped up, but limped off the field.

The Colts were forced to redo the opening kickoff after an offside penalty on the first try. Mathis, only got to the 20 on the first one, but returned the second 84 yards for a touchdown. Mathis, who returned two kickoffs for touchdowns in 2005, broke away from the pack and then cut to the outside to outrun the last two defenders and stroll in for the score.

Slideshow   The Week in Sports Pictures A kayaker flips out, a racehorse eyes the Triple Crown and more. more photos

Clark got in front of Michael Boulware for a 2-yard reception in the back of the end zone to tie it at 7 midway through the first quarter.

Notes: Colts receiver Marvin Harrison had 53 yards on Sunday to move into fourth place all-time in yards receiving with 13,920. ... Manning was 20-of-29 for 273 yards and a touchdown. Addai finished with 22 carries for 72 yards.

NFL game stories Quick look at Week 4 games STEELERS 23, RAVENS 20, OT: Baltimore loses first game of season REDSKINS 26, COWBOYS 24: Dallas can't contain Portis in 1st loss BEARS 24, EAGLES 20: Goal-line stand boosts Chicago JETS 56, CARDINALS 35: Favre throws career-high 6 TDs BUCS 30, PACKERS 21: Ryan's 3 FGs lift Tampa CHARGERS 28, RAIDERS 18: San Diego tops rival 10th straight time BILLS 31, RAMS 14: Buffalo 4-0 for first time since 1992 CHIEFS 33, BRONCOS 19: Johnson rushes for 198 yards for K.C. BROWNS 20, BENGALS 12: Anderson throws TD TITANS 30, VIKINGS 17: Tennessee 4-0 for first time ever PANTHERS 24, FALCONS 9: Smith honors Lucas after TD JAGUARS 30, TEXANS 27, OT: Scobey kicks game winner SAINTS 31, 49ERS 17: McAlister scores first TD of year