Jeff Chiu / AP

The Giants' Barry Bonds hits his 749th career home run off Yankees pitcher Scott Proctor in the eighth inning Friday.

Cain walked the next two batters to load the bases — including Igawa in his first career plate appearance — before Melky Cabrera’s two-run single made it 3-0. That was New York’s second hit in its last 20 at-bats with runners in scoring position. New York added two more runs in the fifth on an RBI double by Bobby Abreu and Rodriguez’s run-scoring single.

Igawa allowed two runs and five hits in 4 2-3 innings after spending the previous seven weeks retooling his delivery in the minors. Igawa had been a big disappointment in his first stint in the majors after the Yankees spent $46 million to bring him over from Japan in the offseason.

But he looked much better this game, holding the Giants scoreless the first four innings, including striking out Bonds in the fourth.

“He was consistent for four innings and to me that’s darn near half the game,” Torre said. “It may have just been the point where you maybe look up at the scoreboard and you see it’s going to be an official game here in a minute and he may have just rushed himself.”

Cain allowed five runs and seven hits in five innings and dropped to 0-5 in his last seven starts. Cain walked four and had no strikeouts for the first time in 53 career starts.

Notes: The Yankees played an exhibition game in San Francisco in 2000. ... Cabrera had to be tended to by the trainer after fouling a ball off his right ankle in the sixth inning. He stayed in the game and tripled. ... Yankees SS Derek Jeter hit an RBI single in the sixth inning to extend his hitting streak to 16 games. He was then picked off first by Randy Messenger. ... Torre tied Leo Durocher for ninth place all-time with 2,009 career wins. ... The crowd of 43,425 was the largest ever for a regular season game at the Giants’ waterfront ballpark that opened in 2000.